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Here's a comprehensive strategy: Step 1: Remove Triggers Start with a low-histamine, low-inflammatory diet: Avoid: Aged cheese, smoked meats, wine, vinegar, fermented foods Leftovers (histamine increases with time) Tomatoes, spinach, avocado, citrus Shellfish Chocolate Alcohol Food dyes, preservatives (especially benzoates) Also Eliminate: Mold exposure (test the home if needed) NSAIDs and other mast cell-activating medications (under supervision) Step 2: Heal the Gut and Support the Microbiome The gut is a major mast cell hub , and healing the gut is essential

Strategies for increasing glutathione include: Consume sulfur-rich foods like cruciferous vegetables Ensure you get adequate and quality sleep Supplements including: alpha-lipoic acid, vitamin C, and NAC Use turmeric in your cooking or take it as a supplement These are helpful strategies to enhance glutathione, combat oxidative stress, and, in my opinion, protect the brain

May 1994;44(5):796-800

Nanoscale 10 , 1075810834, (2018)