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A) Intraperitoneal glucose tolerance test (IPGTT) in wild-type (WT) mice

(14) The mechanisms underlying this potential action might involve IGF-1-mediated suppression of muscle cell-specific enzymes referred to as E3 ubiquitin ligases, including atrogin-1 and muscle ring finger protein-1 (MuRF1)

Such changes could enable healthcare systems to strengthen early obesity prevention programs, diagnosis, and treatment, integrate pharmacological therapy into primary healthcare, and shift from managing long-term complications to more effective preventive approaches