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Prolonged-acting GLP-1 analogs Exenatide LAR or exenatide once weekly is a prolonged-acting GLP-1 analog (median half-life=2 weeks) in which exenatide is incorporated into a 0.06 mm diameter microsphere composed of poly (D,L-lactic-co-glycolic acid) [66]

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Mitochondrial turnover is controlled by signaling molecules such as Bcl-2, which inhibit apoptosis and BAD/BAX signaling, which induces apoptosis and mitophagy

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