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We have demonstrated the beneficial effect of G49, a dualAG, in resolving metabolic-dysfunction associated steatohepatitis (MASH) and improving liver regeneration under this pathological condition in C57BL/6J mice by targeting multiple homeostatic mechanisms including inflammation, oxidative/endoplasmic reticulum stress, mitochondrial dysfunction, and shifting glucose metabolism 13

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The preparation of mushroom extracts or bioactive compounds from mushroom fruiting bodies or mycelia involves several steps, namely pretreatment, isolation and purification ( -glucan degradation, while higher temperatures (above 150C) can disrupt the triple-helix structure and thus cause a decrease in bioactivity