The primary treatment option for this condition is drug therapy using selective serotonin reuptake inhibitors (SSRIs)
These pro-inflammatory factors further damage the barriers and alter the microbiota, perpetuating the cycle of chronic inflammation ( Bacteroidetes and Firmicutes , and an upturn in Proteobacteria ( CB , FP , Clostridium lavalense , Clostridium cluster XlVa , Blautia faecis , Bacteroides uniformis , Ruminococcus torques , and Roseburia inulinivorans ( Based on existing research, intestinal Clostridium and their metabolites exert effects on IBD mainly via intestinal barrier repair, innate immunity regulation, and adaptive immunity modulation ( Clostridium -containing preparations also exhibit certain adjuvant therapeutic effects (69)
[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Pieber TR, Bode B, Mertens A, Cho YM, Christiansen E, Hertz CL, et al
Miao Y, Chen Y, Xue F, Liu K, Zhu B, Gao J, et al