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TRESIBA may cause serious side effects that can lead to death, including: Low blood sugar (hypoglycemia)

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Glutamate cysteine ligase (GCL) is the rst and rate-limiting enzyme in glutathione biosynthesis and its activity is of high im- portance for maintaining glutathione levels in the cells.[22] e second step in GSH synthesis is catalyzed by GSH syn- thetase (GS)

Neuroprotective effects are also thought to be due to its selective binding to glutamate receptors (2)