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Variability in extraction and quantification methods Another significant challenge is the inconsistent composition of bioactive compounds in Schisandra chinensis extracts, which can vary depending on factors such as geographical location, harvest time and processing methods [1, 9, 100]

416 Experimental models of depression also demonstrate uncoupling of astrocytic syncytia, whereas pharmacological inhibition of gap junctions by intracerebral infusion of carbenoxolone induced anhedonia and anxiety-like behaviour

Cost-efficiency extends beyond the unit price

Comments submitted after July 9 but before the July 22 docket closure will still be considered by FDA, but will not go directly to the Committee