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For me, the earliest changes showed up in my appetite, followed by visible weight loss between the first and third month, with more significant changes appearing after six months and beyond

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Ferraro F, Lymperi S, Mndez-Ferrer S, Saez B, Spencer JA, Yeap BY, Masselli E, Graiani G, Prezioso L, Rizzini EL, Mangoni M, Rizzoli V, Sykes SM, Lin CP, Frenette PS, Quaini F, Scadden DT