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Description

This article explores the evidence, practical strategies, and guidance on when to seek medical advice

Aging 38, 110

Clinical Evidence Pivotal Studies and Protocol Selected Studies Description of Studies Four placebo-controlled, double-blind (DB) randomized controlled trials (RCTs) STEP 1 (N = 1,950), STEP 2 (N = 1,210), STEP 3 (N = 611), and STEP 4 (N = 803) compared semaglutide 2.4 mg to placebo, and 1 open-label RCT compared semaglutide to liraglutide and placebo (STEP 8, N = 338), all over 68 weeks of treatment