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Collins, L
Clin Genitourin Cancer 18(2):e145e156 Zygulska AL, Krzemieniecki K, Sowa-Staszczak A (2012) Hypothyroidism during treatment with tyrosine kinase inhibitors
While often temporary, this increase in platelets carries serious risks: Deep vein thrombosis (blood clots in deep veins, usually in legs) Pulmonary embolism (blood clots in lungs) Arterial thrombosis (clots in arteries) Cerebrovascular events (strokes) Coronary artery thrombosis (heart attacks) Splanchnic vein thrombosis (clots in abdominal veins) The risk is particularly high in: Elderly patients Those with pre-existing heart disease Patients with inherited blood-clotting disorders Immobilized individuals Those with hardened arteries Neurological Symptoms and Joint Pain Paradoxically, B12 replacement can temporarily worsen or trigger new neurological symptoms
[6] If you belong to any of these groups and experience symptoms of B12 deficiency, you may need to consult your doctor about taking a blood test
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