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10 Reduced glutathione is associated with higher oxidative stress, 11 which contributes to damage 12 in the trabecular meshwork cells and retinal ganglion cells, worsening glaucoma and accelerating optic nerve damage

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Most studies were brief and used dosages within the upper consumption limits, even though no significant adverse effects were documented in the supplementation trials that were part of this analysis

Additionally, in the DHE staining results, we observed that FOXO4-DRI treatment effectively reduced the ROS levels in the aorta of aged mice (Figure 2F)