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The above results indicate that in the ovaries, CXCL10 can bind to IL18R1 to induce downstream AKT FOXO3A activation, which subsequently promotes the transcription of genes for PMF activation (Fig

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26 ChidambaramS

The included patients had T2DM and proven cardiovascular disease and were at least 50 years old, with glycated hemoglobin levels of 6.58.0 % when treated with stable doses of one or two oral antihyperglycemic agents (metformin, pioglitazone, or a sulfonylurea) or insulin (with or without metformin)