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The authors KK, KR declared that they were an editorial board member of Frontiers at the time of submission

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Studies demonstrate that semaglutide primarily reduces fat mass while preserving muscle tissue, with approximately 65% of weight loss coming from fat reduction.[6] Recent clinical trials show that combining semaglutide with resistance training and adequate protein intake can preserve 50-80% of lean mass that might otherwise be lost during weight reduction

Some users with severe side effects from these GLP-1 drugs have reported vision loss, multiple trips to the ER, corrective surgeries, depression, and other serious consequences