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Souchet, Benoit, Fayal Guedj, Zsuza Penke-Verdier, Fabrice Daubigney, Arnaud Duchon, Yann Herault, Jean Charles Bizot, et al

While directly measuring neuroprotection in living patients is technically unfeasible, alternative strategies, such as monitoring pro-inflammatory markers or neuroprotective cytokines in the plasma of patients receiving istradefylline, could offer valuable mechanistic insights and serve as surrogate indicators of therapeutic activity [485]

A review in the International Journal of Molecular Sciences described GHK-Cu as able to reset gene expression to a healthier, more youthful state in damaged or aged cells

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