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Finally, GSH deficiency contributes to oxidative/nitrosative stress, a condition actually connected with the pathogenesis of many diseases, including cancer, diseases of aging, cystic fibrosis, infection and neurodegeneration

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Cascade process of excitotoxic neuronal death Excessive Ca influx disrupts Ca homeostasis, overwhelming mitochondrial buffering via the uniporter

The primary safety advantage is the lack of IGF-1 elevation