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With GLP-1 usage expanding rapidly amid Indias mounting metabolic disease burden, the advisory signals CDSCOs intent to draw clearer boundaries around ethical promotion and prevent consumer manipulation, particularly of vulnerable populations

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It can also activate transient receptor potential vanilloid 1 (TRPV1) channels, altering visceral pain thresholds, and participate in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis and stress responses

Cons Compounded formulations are not the same as FDA-approved brand products, and long-term trial data are limited