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3.2 COX-2 in leishmaniasis 3.2.1 The hazards of leishmaniasis Since the WHO first recognized leishmaniasis as a neglected tropical disease and the second leading cause of parasite-related death, more than 1 billion people in 98 countries still face a risk of contracting this disease ( Depending on the type of leishmaniasis, symptoms may include fever, weight loss, and partial or total destruction of the mucous membranes of the nose, mouth, and throat ( In 2020, most VL cases were diagnosed in Brazil, Ethiopia, India, Kenya, Somalia, and Sudan ( According to one estimate, 500,000 patients are first infected with VL each year, and approximately 12 million people are infected with Leishmania parasites ( L
[DOI] [PMC free article] [PubMed] [Google Scholar] 182.Zehiroglu C., Ozturk Sarikaya S.B
The upregulated GPX4 was identified as a likely target molecule in targeted therapy for CRC persister cells
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