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Compared to bupropion-naltrexone, patients on GLP-1 agonists medication had nine times higher risk of pancreatitis (inflammation of the pancreas), four times higher risk of bowel obstruction (food is prevented from passing through the small intestine) and three times higher risk of stomach paralysis

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doi: 10.1038/s41467-019-09277-9 69 MiessHDankworthBGouwAMRosenfeldtMSchmitzWJiangMet al