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Vehicle-treated SGm exposed to 15 Gy irradiation exhibited a 3.3-fold increase in the number of H2AX foci per nucleus, indicating a significant increase in double-stranded DNA breaks due to radiation exposure (Fig

There was a validation study out of the Cedars-Sinai, and it's presented at EDW this year that essentially had three groups of people, right

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Most patients experience onset between days 3 and 21 after their first injection or oral dose, with the highest incidence occurring during the first dose escalation phase