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Diabetes Obesity Metab 26(4):15191523 Mosenzon O, et al (2019) Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial
Upon successful binding of GLP-1, receptor-bound adenylyl cyclase will catalyze the conversion of ATP to cyclic AMP (cAMP), leading to subsequent activation of protein kinase A (PKA) and the exchange protein directly activated by cAMP (EPAC) family
Cng dng chnh: Gii c cho c th v tng cng chc nng ca gan
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