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We will also address any questions you may have along the way

21 :110-112 Key words: diabetes, cardiovascular outcome trial, semaglutide Licensing requirements for new antidiabetic drugs changed in the USA following the rosiglitazone controversy, and between 2008 and 2020 a dedicated randomised controlled cardiovascular outcome trial (CVOT) was usually required either before or after licensing

The Medicines and Healthcare products Regulatory Agency (MHRA) has approved its use in the UK, and NICE guideline NG28 supports its use in specific clinical circumstances for adults with type 2 diabetes

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