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doi: 10.1080/21604851.2025.2554040 66 HoltM

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This only applies to those taking Mounjaro and is especially important for the four weeks after starting Mounjaro and after any dose increase. The MHRA characterized its announcement as a reminder, as the decreased effectiveness of birth control pills is already one of several known risks included in Mounjaros package inserts, which includes the following warning with its product: If you take birth control pills by mouth, talk to your healthcare provider before you use Mounjaro

In contrast, GLP-1RAs are designed to resist degradation by DPP-4, enabling sustained high plasma concentrations and prolonged systemic effects