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If the medication gets too hot or freezes, the proteins in the formula can break down, making the treatment less effective or entirely inactive

Keeping your medication cold preserves the molecular structure that allows it to bind to GLP-1 receptors in your brain and pancreas, signaling fullness and regulating appetite

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(3) Disruption of membrane integrity: -syn interacts with the Translocase of the Outer Mitochondrial Membrane (TOM) complex (e.g., TOM40, TOM20) and the Voltage-Dependent Anion-Selective Channel 1 (VDAC1), which leads to abnormal membrane permeability (McCarthy et al., 2022)