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A total of 564 eligible patients were randomized CRT group (284): 45 Gy in 25 fractions + capecitabine 900 mg/m BID on weekdays IrCRT group (280): Same radiotherapy dose + capecitabine 650 mg/m BID weekdays + irinotecan 60 mg/m IV weekly for 4 weeks Most patients were male (66%) with a median age of 61 years (range 2483)

Hexarelin may contribute to the repair of bones and improvement of mineral density, which are crucial for maintaining bone health as we age

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Patent protections for semaglutide the active ingredient in Ozempic and Wegovy are already lapsing in several major markets in 2026, and a tentative FDA approval for a generic injectable version was granted to Apotex and Orbicular earlier this year