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This post-translational modification inhibits PDIs catalytic activity, impairing its role in protein folding

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Cholinergic pathways in the basal forebrain and hippocampus are necessary for attention, learning and memory [164]

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Rector RS, Thyfault JP, Uptergrove GM, Morris EM, Naples SP, Borengasser SJ, Mikus CR, Laye MJ, Laughlin MH, Booth FW, Ibdah JA (2010) Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model

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