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Starting at 2mg gives your body more time to adjust before moving up to stronger doses, which helps minimise side effects

Document clinical contraindication to semaglutide: Persistent nausea or vomiting preventing dose escalation beyond initial doses, a documented thyroid concern (e.g., personal or family history of MEN 2 or medullary thyroid carcinoma), or another clinically documented intolerance can serve as the basis for the exception request

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Like a furnace uses fuel to generate heat, mitochondria use nutrients to generate energy