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In order to prevent this phenomenon, catalase (another antioxidant enzyme) which is abundant in the peroxisomes breaks down H2O2 into water and molecular oxygen, consequently curtailing free radical-induced damage (Fig

Similar content being viewed by others Introduction Drug-induced liver injury have now gradually become the leading causes of acute liver failure in developed countries and acetaminophen (APAP) abuse is the predominant cause of drug-induced hepatotoxicity with associated acute liver failure (Fisher and Curry 2019