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Description

Molecular mechanisms and potential clinical significance of s-glutathionylation

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Microglia populate the CNS during early embryogenesis and primarily function in the phagocytosis of cellular debris, synaptic pruning during neurodevelopment and maturation, and the release of cytokines and growth factors that influence neuronal survival and plasticity (Ginhoux and Prinz, 2015)

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Hence, the cysteine groups are main target for ROS and RNS (Sen and Packer, 2000

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McClean PL, Jalewa J, Holscher C

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