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The nausea is often dose-dependent and timing-dependent
Numerous studies and recent guidelines indicate that while this mechanical stimulation can increase defecation frequency, it does not significantly improve global IBS symptoms and may even exacerbate bloating, gas, and abdominal pain upon initial intake (187, 188)
Participants also incorporated an improved diet and exercise during the trial
Some women find that a moderate-carbohydrate approach, with total carbohydrate intake around 100 to 150 grams daily timed primarily around exercise, optimizes both peptide effectiveness and menopausal symptom management
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