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Thus, MCP-1 may be involved in macrophage recruitment into the lungs in smokers

In a comparative study the size dependency of BBB uptake and permeability was investigated for nanoparticles from 50 to 500 nm of various composition (polystryrene, protein, lipid) on a human culture BBB model in which transferrin nanocarriers with 500 nm diameter showed the most successful BBB penetration [61]

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The first also has licorice root to avoid while pregnant, but isnt a concern while nursing