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In detail, in the young WT versus Mda5 -/- regions, we found NFY (nuclear transcription factor Y,1e-49), KLF1 (Krueppel-like factor 1, 1e-47), SP1 (specificity protein 1, 1e-38), FLI1 (friend leukemia integration 1,1e-21) in the reduced regions and ZSCAN1 (zinc finger and SCAN domain containing 1), P53 (both 1e-02) in the induced regions (Fig