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[1] TB-500 is more tangled still: the genuine human randomized-trial data in this pair belongs to full-length thymosin beta-4 delivered as an eye drop for dry eye not to the injectable fragment that suppliers actually label TB-500. [9] Neither compound is approved by the U.S

However, it's important to note that individual results may vary, and benefits may take several weeks or months to become visible

The broader NNMT-as-therapeutic-target hypothesis is supported by knockdown and knockout studies, but small-molecule pharmacological validation in humans is pending

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