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The advisory emphasises that "decisions about how quickly or slowly to titrate therapy should be guided by an individual's needs." This requires precise, ongoing body composition data, not just weight

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The EGCG group showed a significant reduction in total fibroid volume, a 32.4% reduction in fibroid-specific symptom severity, and a significant decrease in average menstrual blood loss (from 71 mL/month to 45 mL/month) compared to the control group, in which fibroid volume increased by 24.3%. Proposed mechanisms: EGCG inhibits the proliferation of leiomyoma cells, induces apoptosis, and suppresses ER expression