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Previous research has suggested that hepatic GJ proteins might facilitate the spread of free radicals, thereby exacerbating the severity of drug-induced liver damage (Patel et al

found that ZDHHC3 mediates the palmitoylation of IRHOM2 at C476, thereby inhibiting TRIM31-mediated ubiquitination and degradation

Recently, a role for cytoskeleton protein filamin A (FLNA) in DRD2 and SSTRs receptors expression and signaling in PRL- and GH-secreting tumors, respectively, has been demonstrated, first revealing a link between FLNA expression and responsiveness of pituitary tumors to pharmacological therapy

This recent study identifies an miRNA that targets CPT1A as a potential biomarker for therapy