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Moreover, as lysosomal function is essential for mitophagy, impairment in the fusion of lysosomes with autophagosomes-containing mitochondria may compromise the clearance of dysfunctional mitochondria, resulting in exacerbated APAP hepatotoxicity

In terms of reduction in body weight, 10 studies (with 339 and 301 participants from the experimental and control groups, respectively) were included for analysis

These findings are particularly exciting because they suggest GLP-1s may have neuroprotective effects that may help improve the quality of life in patients with Parkinsons disease