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The ketone metabolite -hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease

Clin Chim Acta 204:263277 Hoffmann GF, Athanassopoulos S, Burlina AB, Duran M, de Klerk JB, Lehnert W, Leonard JV, Monavari AA, Muller E, Muntau AC, Naughten ER, Plecko-Starting B, Superti-Furga A, Zschocke J, Christensen E (1996) Clinical course, early diagnosis, treatment, and prevention of disease in glutaryl-CoA dehydrogenase deficiency

Its like giving the liver more of the tools it needs to do its job when it is bogged down

We know that long-duration proton pump inhibitor (PPI) use is often associated with lower magnesium levels and deficiency. Meacham says