glutathione ovarian cancer Carbon monoxide sensitizes cisplatin-resistant cell lines toward cisplatin via attenuation of levels of and nuclear metallothionein Involvement of glutathione peroxidases in

Inhibition of glutathione metabolism by BSO decreased the ESCC tumor burden To investigate whether glutathione metabolism contributed to the progression of ESCC development, we treated mice bearing ESCC 20 weeks after initial carcinogen treatment with buthionine sulfoximine (BSO), a commonly used chemical inhibitor of -glutamylcysteine synthetase (-GCS) that decreases tissue glutathione concentrations (Figure 3a)

The MTT, flow cytometry, and wound healing assays were used to investigate cell viability, cell cycle, and cell migration, respectively

Early recognition and treatment are crucial to prevent irreversible neurological damage

Sources: Huang Y, et al