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Why Opioids Backfire With Repeated Use With repeated exposure, the nervous system adapts to opioids, leading to: Tolerance , requiring higher doses for the same effect (33,35) Dependence , with withdrawal symptoms when doses wear off (35) Opioid-induced hyperalgesia , a paradoxical increase in pain sensitivity (33,36) Rather than calming pain long term, opioids can sensitize the nervous system, making everyday stimuli feel more painful (33,36)

Endometriosis lesions create an inflammatory environment in the pelvis, releasing prostaglandins and cytokines that stimulate nearby nerves

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As a doctor, I often describe collagen as a protein made up of amino acids that acts like the glue of the human body, providing essential structural support