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It is the second-largest retail mortgage originator in the United States, originating one out of every four home loans, [11] and services $1.8 trillion in home mortgages, one of the largest servicing portfolios in the U.S

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Factors such as alcohol-mediated induction of CYP2E1, ALDH2 deficiency, and impaired liver function can further elevate acetaldehyde levels and reduce its clearance

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