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GLP-1 agonists and sexual behavior In a prior publication, we highlighted an analysis by Vestlund and Jerlhag of sexual behavior in male mice which showed that the presence of Ex4, a potent and selective GLP-1 agonist, in the laterodorsal tegmental area (LDTg) was correlated with a decrease in sexual interaction behaviors [29,30]

Clinical trials (STEP programme) have demonstrated that Wegovy can lead to significant weight losswith participants achieving an average of approximately 15% weight loss at 68 weeks when combined with lifestyle modifications

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These findings suggest GLP-1 medications may have neuroprotective properties, potentially slowing or preventing cognitive decline