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I experienced the worst vomiting 48 hours after my first dose every hour for 8 hours

J Affect Disord (2020) 261:1112

Appetite Regulation Through Brain Signaling When these medications activate GLP-1 receptors in the brain, particularly in the hypothalamus (the bodys main center for hunger regulation), several important effects occur: Reduced hunger signals Increased feelings of satiety (fullness) Decreased food cravings, particularly for high-calorie foods Modulation of the brains reward response to food This neurological impact helps patients make more mindful food choices without the intense hunger that often derails weight management efforts

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