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Oxidative stress is essentially an internal imbalance where unstable molecules, known as free radicals, cause damage to your cells and tissues

Frosst, P., Blom, H.J., Milos, R., Goyette, P., Sheppard, C.A., Matthews, R.G., Boers, G.J.H., den Heijer, M., Kluijtmans, L.A.J., van den Heuve, L.P., Rozen, R

In either case, having moved into the nucleus, the modified (activated) transcription factor interacts with its corresponding cis-acting element on target promoters to regulate gene expression

Quantification of the peaks showed that a quarter of TGP-fusion protein was degraded, which means the gap between the expression yields could have been larger had the degradation be controlled