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Weight loss from GLP-1 medications can be rapid (typically 5-15% of body weight over several months), and MS patients must ensure adequate protein and micronutrient intake to support neurological function, immune regulation, and muscle preservation

Through systematic analysis of clinical trials, meta-analyses, and emerging evidence from landmark studies like SELECT, this paper evaluates whether GLP-1 agonists represent a transformative breakthrough or an overhyped intervention with significant limitations

The weight regain reality Clinical data shows that patients who discontinue semaglutide regain approximately two-thirds of their lost weight within one year

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