"We don't even know the whole effect of the side effects," he said
however, these events remained relatively uncommon, affecting fewer than 5% [13, 40, 42, 4446] and 1% [13, 39, 42, 44] of semaglutide-treated participants, respectively
In the UK, NICE guidance specifies that these medications should only be prescribed within specialist weight management services and for people meeting specific BMI thresholds (typically BMI 35 kg/m with weight-related comorbidities or 40 kg/m without), alongside diet and physical activity interventions
Participants receiving weekly 2.4mg doses of semaglutide lost an average of 14.9% of their body weight over 68 weeks. That's a significant amount and this kind of rapid change is known to trigger telogen effluvium in some people