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GI adverse events reported but detailed rates not yet fully published

Annu Rev Biophys 41:227246 Valds-Mas R, Gutirrez-Fernndez A, Gmez J, Coto E, Astudillo A, Puente DA, Reguero JR, lvarez V, Mors C, Len D, Martn M, Puente XS, Lpez-Otn C (2014) Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy

Individual experiences and clinical outcomes vary

Results showed that GLP-1 receptor agonists and SGLT2 inhibitors were superior in reducing the risk of MACE when compared to DPP-4 inhibitors (HR 086 [082089] and 086 [082090], respectively), but no difference was found between SGLT2 inhibitors and GLP-1 receptor agonists in reducing rate of MACE (HR of 101 (094107)) (68)