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Id long thought of lifting weights as essential for athletic performance, regardless of your sport, but I hadnt considered the impact on healthy aging

In type 2 diabetes, the liverpancreas circuit is disrupted, in part due to reduced hepatic insulin sensitivity and clearance, eventually resulting in hyperglycemia and hyperinsulinemia

Key data point: in the retatrutide fatty-liver study, Sanyal and colleagues (Nature Medicine, 2024) reported liver fat falling 80 to 90 percent over 48 weeks in patients who started with fatty liver disease, a drop tied closely to the weight and belly-fat loss and, in theory, to glucagon-receptor-driven fat burning in the liver

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