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Additionally, GLP-1 RAs have been demonstrated to activate AP-1, which regulates the expression of apoptotic genes, and to phosphorylate Bad, a pro-apoptotic factor, thereby reducing apoptosis [47] (Fig

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A study(13)was conducted on murine models with experimentally injured gastrocnemius muscle complex

Metformin) with diagnosis of type 2 diabetes Documented history of lifestyle intervention Quarterly clinical review to assess improvement (weight loss or A1C) Discontinuation if there is no measurable improvement after 6 months 3