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Side effects vary by compound but the most commonly reported across the class include water retention (particularly with CJC-1295 and other GH-stimulating peptides), increased hunger (most pronounced with GHRP-6 due to its stronger ghrelin activity), mild injection site irritation, and temporary fatigue in the first week of use

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However, there are currently fewer mechanisms for regulating ROS in T cells, so it is still difficult to explain how the altered systemic metabolic environment after obesity affects T cells in the context of the immune response

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