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Results The loss of germline induces transcriptomic changes in the GSC niche DTC at the end of the distal gonad in worms forms the niche encasing GSCs (Kimble and White, 1981)

Publisher | Google Scholor Sun L, Shang B, Lv S, Liu G, Wu Q, et al

however, p38 MAPK exerts a positive regulation on PGC1, and MAPK1 along with MAPK14 promote both starvation- and hypoxia-induced mitophagy in HeLa cells ( FIGURE 2 On the other hand, in addition to its well-known functions, PGC1, a master regulator of mitochondrial biogenesis, positively regulates mitophagy by directly inducing the expression of transcription factor EB (TFEB) that mediates lysosomal biogenesis (Settembre et al., 2011)

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