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Several indirect mechanisms may explain why some individuals notice changes in urine odour whilst taking Wegovy, most of which relate to the metabolic and dietary changes accompanying significant weight loss rather than the medication itself

10.1111/j.1468-2982.2005.01059.x Cephalalgia 54 SteinerT

Loss of both adipose tissue and lean muscle mass may reduce the natural cushioning and support around the spine, potentially leading to discomfort until the musculoskeletal system adapts to the new body composition

4.3 Ferroptosis in retinal ganglion cells RGCs constitute neuronal populations situated in the inner retina that are responsible for converting light signals into neural pulses and transmitting them to the visual center of the brain (183)